Glutamine is an amino acid that is present in our bodies.  Amino acids are the blocks that help build protein. Glutamine is produced in the muscles and is then distributed by the blood to all the organs that need it. Glutamine also helps gut function, the immune system, and other essential processes in the body, especially at times when you are stressed out. Glutamine also helps body to make other amino acids and glucose (sugar).

Some people use glutamine for digestive system conditions such as stomach ulcers, ulcerative colitis, and Crohn disease. It is also used to cure depression, irritability, anxiety, insomnia, moodiness and enhancing physical performance of body. It is used for attention deficit-hyperactivity disorder, a urinary condition called cystinuria, sickle cell anemia, and for alcohol withdrawal support. For commercial use it is made by a fermentation process using bacteria that produce glutamine.

Effective uses of L-Glutamine:

1. Glutamine plays a key role in cell volumizing, helps increase ability to secrete human growth hormone, and metabolizes fat and also has anti-catabolism abilities.

2. Glutamine also helps to reduce infections, and improve wound healing in people with burns.

3. It keeps bacteria from moving out of the intestine and infecting other parts of the body after major injuries.

4. Taking glutamine by mouth helps HIV/AIDS patients absorb food better and gain weight. Doses of 40 grams per day are advisable to produce the best effect.

5. Some evidence suggests that glutamine also reduces soreness and swelling inside the mouth caused by chemotherapy. Some researchers say that chemotherapy patients who do not have enough glutamine to start with are most likely to be helped.

Some possible side effects of L-Glutamine:

1. People with Cirrhosis should avoid L-Glutamine supplements because it could worsen the condition and produce negative results.

2. It also causes some mental changes in people with mania.

3. Women who are pregnant and are breastfeeding mothers should avoid its use to prevent detrimental effects.

4. In cases of severe liver disease with difficulty thinking or confusion glutamine could make this condition worse.

5. If you are sensitive to MSG, you might also be sensitive to glutamine, because the body converts glutamine to glutamate. Therefore avoid its use if your problem persists.


1. Use exactly as directed on the label, or as prescribed by your doctor. Do not use in larger or smaller amounts or for longer than recommended. When treating short bowel syndrome, you may need to take glutamine 6 times per day for up to 16 weeks. The number of times per day you take glutamine depends on the reason you are using it. Always follow your doctor's instructions.

2. Take glutamine tablets on an empty stomach, at least 1 hour before or 2 hours after a meal. Glutamine may be only part of a complete program of treatment that may also include a special diet, tube feedings, and IV fluids. It is very important to follow the diet and medication plan created for you by your doctor or nutrition counselor.

3. Store at room temperature away from moisture and heat. Keep each dose of the oral powder in its packet until you are ready to use the medicine. An overdose of glutamine is not expected to produce life-threatening symptoms.